The American Society for Reproductive Medicine (ASRM) provides detailed guidance for individuals and couples preparing for pregnancy. Key recommendations, focusing on both general preconception health and fertility considerations, are summarized here.
Meet with your OB/GYN or reproductive specialist to review medical history, medications, vaccinations, and lifestyle. Prenatal Vitamins and Folic Acid
Take 400–800 mcg (0.4-0.8 mg) of folic acid daily starting at least one month before conception to prevent neural tube defects. Most over-the-counter prenatal vitamins contain this amount of folic acid. Some women may need more (e.g., those with epilepsy, diabetes, or a previous child with a neural tube defect). Speak with your OB/GYN or reproductive specialist for specific recommendations.
Conditions like diabetes, thyroid disorders, hypertension, asthma should be well-controlled before conception. Mental health is also important—seek support if needed for anxiety, depression, etc.
Review all current and recent medications with your OB/GYN or reproductive specialist. Some prescription and over-the-counter medications or herbal supplements may not be safe during pregnancy. The organization, "Mother To Baby", can provide guidance on the safety of medications in pregnancy and when trying to conceive. More information can be found on their website: www.MotherToBaby.org
All couples should consider screening for being a carrier of cystic fibrosis. Specific ethnic groups may consider specialized testing including:
Ensure vaccinations are up-to-date, particularly for rubella, varicella, Tdap, hepatitis B, COVID-19, and influenza.
Chronic stress can impact fertility and overall well-being. Consider mindfulness, yoga, therapy, or whatever works best for you.
